摘要 : Background and Objective: Formalin can be credited for raising the number of patients with kidneys failure, which is increasing in incidence in Egypt annually, according to WHO and the Egyptian Ministry of Health. Lemon grass C...
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Background and Objective: Formalin can be credited for raising the number of patients with kidneys failure, which is increasing in incidence in Egypt annually, according to WHO and the Egyptian Ministry of Health. Lemon grass Cymbopogon schoenanthus (CS) is highly reputed in Egyptian folk medicine as an effective renal antispasmodic and diuretic agent. This study aimed to use the CS extract to eliminate the formalin hazard in rats. Materials and Methods: The experiment was designed and rats divided into six groups are group 1 (untreated) served as control group; group 2 received formalin solution, group 3 and 4 orally treated with CS extract at different two doses (50 and 100 μL). Groups 5 and 6 received formalin solution plus CS extract at mentioned doses. The changes in rat's body weight were noted and the biochemical blood parameters were determined as well as histopathological examination of liver and kidney. Results: The results indicated that all tested biochemical parameters were in normal value for the control group and had no significant differences for CS groups. While, the animals treated with formalin at dose of (100 mg kg -1 b.wt.) showed significant increase in tested biochemical parameters compared with control and CS groups. Conclusion: It is worthy to mention that the rats treated with CS plus formalin showed significant changes in all tested parameters compared with the group received formalin alone. The histopathological examination confirmed the blood biochemical analyses and treatment with CS extract improved the liver and kidney tissues.]]>
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Background and Objective: The prevalence of obesity is increasing both worldwide and locally in India. It is considered a major health problem and often leads to other associated diseases such as type 2 diabetes, ischemic heart di...
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Background and Objective: The prevalence of obesity is increasing both worldwide and locally in India. It is considered a major health problem and often leads to other associated diseases such as type 2 diabetes, ischemic heart diseases, stroke and cancer. In the present study, the effects of powder of Rosa damascena flowers on high-fat diet-induced obesity in Wistar albino rats were examined. Materials and Methods: Female Wistar albino rats fed with a High Fat Diet (HFD) (p.o) for 6 weeks were used to induce obesity. Powder of R. damascena (214 mg kg~(?1) b.wt.) petals administered orally to HFD-fed rats for 6 weeks. Physiological parameters like body weight, food and water intake, fat pad analysis and biochemical parameters like serum lipids, glucose, Serum Glutamate Oxaloacetate Transaminase (SGOT) and Serum Glutamate Pyruvate Transaminase (SGPT), serum urea and creatinine levels were measured. Results: Treatment with powder of R. damascena flower petals to HFD-induced obese rats resulted in a significant reduction in body weight gain, fat pads, serum lipids, glucose, SGOT, SGPT and creatinine levels as compared to rats fed HFD alone. Further, the extract also showed a significant increase in High-Density Lipoprotein (HDL) levels. Conclusion: These results exhibit that the R. damascena flower possesses significant anti-obesity potential.
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The objective of the study was to determine interval values of biochemical parameters in the most commonly applied experimental model among different species, i.e. rats. Blood analysis of experimental animals is done in different ...
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The objective of the study was to determine interval values of biochemical parameters in the most commonly applied experimental model among different species, i.e. rats. Blood analysis of experimental animals is done in different research fields. They are important especially in experiments in pharmacology, pathophysiology, experimental surgery, toxicology and for monitoring experimental disorders in laboratory animals. In this paper, basic biochemical markers in the blood serum of Buffalo and Wistar rats are also compared in relation to the animals' age and sex. The values were obtained using the latest available measurement methods and the above-listed checkpoints were considered. The biochemical markers show variability between the particular groups of animals related to their age, sex, and strain. The obtained data may be used to create a model of interval values of biochemical parameters for the Buffalo and Wistar rat strains. This study is necessary to enhance our understanding on basic parameters in these animals which are often used in different medical experiments.
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In the post helminth infection, proteins and related molecular changes have been studied in the myotomal muscles of Channa punctatus due to the intestinal infection by Genarchopsis goppo Ozaki (1925) and liver infection by Collodi...
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In the post helminth infection, proteins and related molecular changes have been studied in the myotomal muscles of Channa punctatus due to the intestinal infection by Genarchopsis goppo Ozaki (1925) and liver infection by Collodistomum diaphanum Odhner (1902), on the protein metabolism of the myotomal muscles Various biochemical parameters that have been investigated are total proteins, sucrose soluble proteins. sucrose insoluble proteins. albumins, globulins and free amino acids. All these parameters that have been assayed showed an increase in the liver than to the intestine. The increase in the content of substrate and the activity levels of enzymes suggest that in the liver the rate of protein metabolism is greatly enhanced than to the intestine. These indicate that liver plays an active role in smoothening the fluctuations of metabolism, generated by helminth worms. The increase in the various biomolecules indicates biochemical adaptations of hosts to the parasitic adaptations.
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Hepatic disorders are commonly encountered in canines and the clinical signs will be expressed only when approximately eighty percent of the liver is affected. Biochemical parameters provide early information for the identificatio...
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Hepatic disorders are commonly encountered in canines and the clinical signs will be expressed only when approximately eighty percent of the liver is affected. Biochemical parameters provide early information for the identification, management and prognosis of hepatic problems. Its relevance was studied in dogs with induced hepatitis and bile duct obstruction and reported.
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The aim of this study was to assess the effect of bifenthrin on common carp (Cyprinus carpio L.). The 96-h LC50 value of Talstar EC 10 (active substance 100 g l(-1) bifenthrin) was found to be 57.5 mu g l(-1). Examination of haema...
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The aim of this study was to assess the effect of bifenthrin on common carp (Cyprinus carpio L.). The 96-h LC50 value of Talstar EC 10 (active substance 100 g l(-1) bifenthrin) was found to be 57.5 mu g l(-1). Examination of haematological and biochemical profiles and histological tissue examination was performed on common carp after 96 h of exposure to Talstar EC 10 (57.5 mu g l(-1)). The experimental group showed significantly higher (P < 0.01) values of plasma glucose, ammonia, aspartate aminotransferase and creatine kinase as well as the relative and absolute monocyte count, compared with the control group. Histological examination revealed teleangioectasiae of secondary gill lamellae and degeneration of hepatocytes. The bifenthrin-based Talstar EC 10 pesticide preparation was classified as a substance strongly toxic for fish.
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The aim of this study was to assess the effect of bifenthrin on common carp (Cyprinus carpio L.). The 96-h LC50 value of Talstar EC 10 (active substance 100 g l(-1) bifenthrin) was found to be 57.5 mu g l(-1). Examination of haema...
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The aim of this study was to assess the effect of bifenthrin on common carp (Cyprinus carpio L.). The 96-h LC50 value of Talstar EC 10 (active substance 100 g l(-1) bifenthrin) was found to be 57.5 mu g l(-1). Examination of haematological and biochemical profiles and histological tissue examination was performed on common carp after 96 h of exposure to Talstar EC 10 (57.5 mu g l(-1)). The experimental group showed significantly higher (P < 0.01) values of plasma glucose, ammonia, aspartate aminotransferase and creatine kinase as well as the relative and absolute monocyte count, compared with the control group. Histological examination revealed teleangioectasiae of secondary gill lamellae and degeneration of hepatocytes. The bifenthrin-based Talstar EC 10 pesticide preparation was classified as a substance strongly toxic for fish.
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Sheep and goat husbandry has always played an important role in swiss agriculture, but in recent years these animals are increasingly appreciated as hobby pets. This opens new diagnostic and therapeutic perspectives for veterinary...
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Sheep and goat husbandry has always played an important role in swiss agriculture, but in recent years these animals are increasingly appreciated as hobby pets. This opens new diagnostic and therapeutic perspectives for veterinary surgeons, notably in the determination of hematological and clinical biochemical parameters. For the current methods used there are no reference range values available for adult sheep and goats kept under swiss conditions. Therefore, the present study was designed to determine haematological and clinical biochemical parameters in 102 goats and 102 sheep from swiss flocks. Significant differences were found between the two species, especially regarding erythrocyte count, mean erythrocyte volume, It hemoglobin content as well as leukocyte count. It is therefore of utmost importance to discriminate between sheep and goats when interpreting laboratory findings.
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Introduction : COVID-19 Pandemic has affected the Healthcare System adversely. It should be diagnosed early to prevent mortality and morbidity. Thus various Haematological and Biochemical markers can be used specially in developin...
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Introduction : COVID-19 Pandemic has affected the Healthcare System adversely. It should be diagnosed early to prevent mortality and morbidity. Thus various Haematological and Biochemical markers can be used specially in developing countries where clinicians have limited access to Molecular Diagnostic Technique. Aim and objectives : The study aims to observe the role of haematological and biochemical parameters in diagnosing as well as predicting the prognosis along the course of the disease. Material and methods : Retrospective study performed in Department of Pathology from April, 2021 to May, 2021 on 200 COVID-19 positive patients. The tests were conducted using the Haematological and Biochemistry Auto analysers. Results : Out of 200 Reverse Transcription Polymerase Chain Reaction (RT-PCR) positive COVID-19 patients analysis of Haematological Parameters showed Leucocytosis, Neutrophilia, Lymphopenia and Eosinopenia. Neutrophil Lymphocyte Ratio, Platelet Lymphocyte Ratio and Systemic Inflammatory Index were also found to be elevated in comparison to the control cases. Statistically significant difference was observed in Total Leucocyte Count, Absolute Neutrophil Count, Absolute Lymphocyte Count, Kidney Function Tests (KFT) and Liver Function Tests (LFT) between severe and non severe cases. Biochemical parameters were found to be more elevated in severe cases. C-Reactive Protein (CRP) levels >50 mg/dl and Lactate Dehydrogenase (LDH) levels >1000U/L were found only in severe cases. Conclusion : Haematological and Biochemical Markers being easily available and reliable can be utilised as useful prognosticator for early prediction of disease. Elevated Neutrophil Lymphocyte Ratio, Platelet Lymphocyte Ratio and Systemic Inflammatory Index can be useful in diagnosing COVID-19 especially when clinical suspicion is present despite negative Polymerase Chain Reaction (PCR) reports.
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The objective of the present study was to report the occurrence of Trypanoxyuris in owl monkeys, using data from clinical and haematological examinations, as well as clinical chemistry (blood urea nitrogen (BUN), creatinine, alani...
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The objective of the present study was to report the occurrence of Trypanoxyuris in owl monkeys, using data from clinical and haematological examinations, as well as clinical chemistry (blood urea nitrogen (BUN), creatinine, alanine aminotransferase (ALT) and aspartate aminotransferase (AST)) of infected and uninfected animals. Twenty animals in apparently good clinical health were studied. The coproparasitological examinations showed eggs compatible with Trypanoxyuris sp. in 50% of animals. The number of red blood cells, haematocrit and haemoglobin levels were significantly higher in the males, compared to the females, irrespective of parasitism. However, comparing segmented neutrophils in infected males and females, a significant difference (P < 0.05) was observed. All blood chemistry values were considered normal for the species pattern, even though significant differences were observed for BUN and ALT in infected males. The infection by Trypanoxyuris sp. did not appear to interfere with the clinical condition of animals.
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